Two percent of the population impacted. - Individuals bearing this gene have a high likelihood of contracting Alzheimer's disease.
This gene is known as "APOE4." A recent study published on Monday indicates that individuals carrying two copies of this gene have a nearly guaranteed chance of developing Alzheimer's disease. Approximately 2% of the population possesses this gene combination.
The team of researchers at the Sant Pau Institute in Barcelona, Spain, has published their findings in the journal "Nature Medicine." They examined close to 10,000 records from the US database "National Alzheimer's Coordinating Center" and five other studies. Individuals with an APOE4 combination exhibited the standard Alzheimer's biomarkers in 95% of cases. These markers included specific proteins present in the cerebrospinal fluid or distinctive plaques in the brain.
Is it possible to get tested for APOE4?
In Germany, APO4 tests primarily occur as part of research studies. If you wish to determine your Alzheimer's risk independently, there are very few options. Home-use ApoE4 tests, such as those available in the United States, are prohibited in Germany due to the Genetic Diagnostics Act. Only in rare instances are there opportunities for ApoE4 testing.
In Germany, most Alzheimer's genetic tests are geared toward familial Alzheimer's disease, which manifests before age 65 and is inherited from either the mother or father. However, these genetic tests are not ApoE4 tests. They concentrate on the presence of other Alzheimer's genes and are exclusively conducted in genetic counseling sessions.
Is there a cure for Alzheimer's disease?
At present, there is no permanent cure for Alzheimer's disease. However, various treatment methods exist:
- Medications that relieve symptoms for some patients in the early stages of the disease. Nonetheless, these drugs cannot halt or reverse the development of this condition.
- Supportive measures: These include occupational therapy, physical therapy, and social assistance.
- A healthy diet, physical activity, and mental engagement can help to slow the progression of the disease.
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Source: symclub.org
