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Cells discard waste to regenerate and show signs of renewed youth, according to a recent research

Cells exhibit a novel mechanism known as cathartocytosis, in which they expel their contents for the purpose of healing.

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"Research suggests that cells expel waste to regenerate and appear youthful once more"
"Research suggests that cells expel waste to regenerate and appear youthful once more"

Cells discard waste to regenerate and show signs of renewed youth, according to a recent research

In a groundbreaking study published in Cell Reports, scientists from Germany have discovered a new cellular process called cathartocytosis, which is akin to vomiting in cells, helping them heal and rejuvenate. This fascinating process was first described by Dr. Jason C. Mills in 2018.

The research was conducted on mice with stomach injuries, aiming to understand how cells heal or fail to heal from infection or inflammatory diseases. During the study, Dr. Jeffrey W. Brown, the first author, noticed debris outside the cells in a mouse stomach injury model, leading to the realization of a previously unknown cellular purge dubbed "cellular cleansing."

Cathartocytosis is part of a larger regenerative injury response called paligenosis, where cells reprogram themselves to revert to an "immature" or young state. This cellular cleanse allows cells to rapidly become small, primitive cells capable of proliferating and repairing injuries.

However, because cathartocytosis is "fast and messy," it might have downsides. It could potentially slow the healing of chronic injuries, cause inflammation, and even contribute to the development of cancer. The study authors suspect that cathartocytosis could actually damage the stomach.

Despite these potential drawbacks, the study authors believe that cathartocytosis allows cells to regenerate healthy tissue. This discovery could lead to new treatment strategies for stomach and GI cancers.

Researchers at Washington University School of Medicine and Baylor College of Medicine have joined the pursuit of understanding this fascinating process. They hope to find ways to use these healing mechanisms in medicine while avoiding the negative effects of cell "vomit."

As research continues, we can look forward to a better understanding of this intriguing cellular process and its potential applications in medicine.

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