Aging well in the future: Discovering the science behind cellular detox, postbiotics, and the rhythm of the body clock
In the realm of cosmetic science, the connection between cellular detoxification and the circadian cycle is gaining significant attention. This relationship is crucial as accumulated toxins can interfere with cellular processes, damage cellular structures, and lead to various health issues.
At the recently concluded 33rd IFCSS Congress, Provital, a renowned ingredient supplier, participated, presenting innovative research on cellular detoxification. While specific details about their presentation on the role of postbiotic ingredients in cellular detoxification and circadian rhythms are not widely available, the broader scientific community acknowledges the potential of postbiotics in this field.
Postbiotics, bioactive compounds produced by probiotic bacteria during fermentation, are being studied for their potential to support skin barrier function, modulate inflammation, and enhance cellular detoxification processes. Emerging research suggests that postbiotics might also influence circadian rhythms in skin cells by interacting with molecular pathways that regulate the skin's natural daily repair cycle.
One such postbiotic is CircanblueTM, a compound derived from Lactococcus lactis ferment lysate. CircanblueTM is being researched for its potential antioxidant activity, ROS scavenging, mitochondria homeostasis, anti-inflammatory activity, and suppression of damage in the skin. It is also found to modulate genes related to the skin's circadian cycle, including a melatonin receptor, MTR1, and a repairing enzyme, SIRT1.
CircanblueTM has been shown to restore the expression rhythm of the genes CLOCK and CRY1 closer to basal levels, indicating its potential in revert the desynchronization of the circadian cycle in keratinocytes caused by blue light. This could be a significant breakthrough as exposure to blue light affects skin's functions and the biorhythm of skin cells, resulting in signs of facial fatigue and aging.
The process of cellular detoxification, a continuous and critical physiological process that ensures cells can maintain their normal function and overall health, is a key focus in this research. Cellular detoxification is activated by CircanblueTM as it modulates genes related to the circadian rhythm, such as Nqo-1 and Hmox1.
In conclusion, while the exact details of Provital’s presentation at the 33rd IFCSS Congress are not fully known, in cosmetic science, postbiotic ingredients are increasingly recognized for their role in enhancing cells' detoxification capacity and modulating circadian rhythms to improve skin health and appearance. This innovative approach represents a potential disruptive approach for well-aging. The current focus on circadian rhythms has brought a new light into cellular detoxification processes, paving the way for future advancements in cosmetic science.
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